\u7761\u7720\u8207\u7c92\u7dda\u9ad4\u80fd\u91cf\u95dc\u806f\u91cd\u9ede\u6458\u8981<\/title>\n<\/head>\n<body>\n\n <p>“2025 [Nature] Mitochondrial origins of the pressure to sleep”<\/p>\n\n <h2>\u7761\u7720\u8207\u7c92\u7dda\u9ad4\u7684\u80fd\u91cf\u95dc\u806f\uff5c\u91cd\u9ede\u6458\u8981\u8207\u5065\u5eb7\u7b56\u7565<\/h2>\n\n <h2>\ud83d\udd2c \u7761\u7720\u58d3\u529b\u7684\u6838\u5fc3\u6a5f\u5236<\/h2>\n <table border=\"1\">\n <thead>\n <tr><th>\u95dc\u9375\u6a5f\u5236<\/th><th>\u8aaa\u660e<\/th><\/tr>\n <\/thead>\n <tbody>\n <tr>\n <td>\u80fd\u91cf\u904e\u8f09 \u2192 \u7761\u610f\u7522\u751f<\/td>\n <td>ATP\u5806\u7a4d\u963b\u585e\u96fb\u5b50\u50b3\u905e\u93c8\uff0c\u81ea\u7531\u57fa\u4e0a\u5347\u5f15\u767c\u7761\u610f<\/td>\n <\/tr>\n <tr>\n <td>\u96fb\u5b50\u50b5\u8207\u7761\u4e0d\u98fd\u5faa\u74b0<\/td>\n <td>\u71ac\u591c\u52a0\u91cd\u7c92\u7dda\u9ad4\u8ca0\u64d4\uff0c\u81ea\u566c\u8207\u4fee\u5fa9\u5ef6\u9072\uff0c\u88dc\u7720\u7121\u6548<\/td>\n <\/tr>\n <tr>\n 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<strong>\u7121\u6cd5\u53ca\u6642\u6d88\u8017<\/strong>\uff0c\u6703\u9020\u6210\uff1a<\/p>\n\n<ul>\n <li><strong>ATP\/ADP \u6bd4\u503c\u904e\u9ad8<\/strong> \u2192 \u6291\u5236\u96fb\u5b50\u50b3\u905e\u93c8\uff08ETC\uff09\u9032\u4e00\u6b65\u904b\u4f5c<\/li>\n <li><strong>\u8907\u5408\u9ad4 I \u8207 III \u96fb\u5b50\u5806\u7a4d<\/strong> \u2192 CoQ pool \u9084\u539f\u904e\u5ea6<\/li>\n <li><strong>\u7522\u751f\u6d3b\u6027\u6c27 ROS<\/strong>\uff1a\u8d85\u6c27\u9670\u96e2\u5b50\uff08O\u2082\u207b\uff09\u3001\u904e\u6c27\u5316\u6c2b\uff08H\u2082O\u2082\uff09\u7b49\u81ea\u7531\u57fa<\/li>\n <li><strong>\u7c92\u7dda\u9ad4\u5167\u819c\u53d7\u640d<\/strong>\uff1a\u6c27\u5316 cardiolipin\u3001\u819c\u96fb\u4f4d\u4e0b\u964d\uff08\u0394\u03c8m\u2193\uff09<\/li>\n <li><strong>\u4ee3\u8b1d\u8b66\u5831\u8a0a\u865f\u555f\u52d5<\/strong>\uff1a\u5982 AMPK \u6d3b\u5316\uff0cSIRT1 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{"id":1223,"date":"2025-07-23T19:59:16","date_gmt":"2025-07-23T11:59:16","guid":{"rendered":"https:\/\/otc.com.tw\/wordpress\/?p=1223"},"modified":"2025-07-24T12:58:16","modified_gmt":"2025-07-24T04:58:16","slug":"%e7%82%ba%e4%bd%95%e6%9c%83%e7%94%a2%e7%94%9f%e7%9d%a1%e6%84%8f-%e7%9b%a7%e9%86%ab%e4%bb%8b%e7%b4%b92025%e5%b9%b4%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/otc.com.tw\/wordpress\/%e7%82%ba%e4%bd%95%e6%9c%83%e7%94%a2%e7%94%9f%e7%9d%a1%e6%84%8f-%e7%9b%a7%e9%86%ab%e4%bb%8b%e7%b4%b92025%e5%b9%b4%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6\/","title":{"rendered":"\u70ba\u4f55\u6703\u7522\u751f\u7761\u610f?! \u76e7\u91ab\u5e2b\u4ecb\u7d392025\u5e74\u6700\u65b0\u7814\u7a76"},"content":{"rendered":"\n\n\n\n \n \n \n \u7761\u7720\u8207\u7c92\u7dda\u9ad4\u80fd\u91cf\u95dc\u806f\u91cd\u9ede\u6458\u8981<\/title>\n<\/head>\n<body>\n\n <p>“2025 [Nature] Mitochondrial origins of the pressure to sleep”<\/p>\n\n 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<li>\u767d\u5929\u904b\u52d520\u5206\u9418\u4fc3\u9032\u7c92\u7dda\u9ad4\u65b0\u751f<\/li>\n <li>\u7761\u524d2\u5c0f\u6642\u9060\u96e2\u85cd\u5149\u4ee5\u5229\u4fee\u5fa9<\/li>\n <li>\u56fa\u5b9a\u77617\u5c0f\u6642\u4ee5\u4e0a\u555f\u52d5\u7dda\u7c92\u9ad4\u9032\u884c\u878d\u5408\u3001mitophagy\uff08\u7c92\u7dda\u9ad4\u81ea\u566c\uff09<\/li>\n <\/ul>\n\n <h3>\ud83d\udca1\u4e2d\u91ab\u7642\u6cd5\u8f14\u52a9\u7c92\u7dda\u9ad4\u4fee\u5fa9<\/h3>\n <ul>\n <li>\u6c34\u85e5\u5e73\u809d\u6cd5\uff1a\u900f\u904e\u8abf\u7bc0\u81ea\u5f8b\u795e\u7d93\u8207\u6297\u767c\u708e\u53cd\u61c9\uff0c\u4fc3\u9032\u7c92\u7dda\u9ad4 ATP \u751f\u6210\u8207\u80fd\u91cf\u4ee3\u8b1d\u7a69\u5b9a\u3002<\/li>\n\n <li>\u5fc3\u8eab\u5206\u6d41\uff1a\u91dd\u7078\u5f8c\u5fc3\u7406\u58d3\u529b\uff08\u7126\u616e\u3001\u5931\u7720\u3001\u8166\u904e\u52de\uff09\u300c\u8f49\u5316\u300d\u70ba\u751f\u7406\u4fee\u5fa9\u53cd\u61c9\u3001 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<strong>\u7121\u6cd5\u53ca\u6642\u6d88\u8017<\/strong>\uff0c\u6703\u9020\u6210\uff1a<\/p>\n\n<ul>\n <li><strong>ATP\/ADP \u6bd4\u503c\u904e\u9ad8<\/strong> \u2192 \u6291\u5236\u96fb\u5b50\u50b3\u905e\u93c8\uff08ETC\uff09\u9032\u4e00\u6b65\u904b\u4f5c<\/li>\n <li><strong>\u8907\u5408\u9ad4 I \u8207 III \u96fb\u5b50\u5806\u7a4d<\/strong> \u2192 CoQ pool \u9084\u539f\u904e\u5ea6<\/li>\n <li><strong>\u7522\u751f\u6d3b\u6027\u6c27 ROS<\/strong>\uff1a\u8d85\u6c27\u9670\u96e2\u5b50\uff08O\u2082\u207b\uff09\u3001\u904e\u6c27\u5316\u6c2b\uff08H\u2082O\u2082\uff09\u7b49\u81ea\u7531\u57fa<\/li>\n <li><strong>\u7c92\u7dda\u9ad4\u5167\u819c\u53d7\u640d<\/strong>\uff1a\u6c27\u5316 cardiolipin\u3001\u819c\u96fb\u4f4d\u4e0b\u964d\uff08\u0394\u03c8m\u2193\uff09<\/li>\n <li><strong>\u4ee3\u8b1d\u8b66\u5831\u8a0a\u865f\u555f\u52d5<\/strong>\uff1a\u5982 AMPK \u6d3b\u5316\uff0cSIRT1 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